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Description

SV388 is a well-characterized cell line that has garnered significant interest among researchers in the fields of virology, oncology, and immunology. Derived from the embryonic tissues of chickens, specifically the bursa of Fabricius, SV388 is often utilized as a model to study various aspects of cell biology and pathology due to its unique properties and characteristics.

Origin and Characteristics

SV388 was initially established in the 1970s from a tumor in chickens, specifically those afflicted with a viral-induced lymphoid neoplasm. The cells are abnormal in nature and capable of continuous growth in vitro, which is a vital feature for laboratory studies. The cell line exhibits characteristics typical of transformed cells, including increased proliferation rates and altered morphology. It is adherent and forms monolayer cultures that contribute to its ease of use in laboratory settings.

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